December is the month for the UKINETs Conference – one last push before the wind down to the Christmas holidays. The day was focused on educating and stimulating discussion on research amongst the many specialities involved in the care of patients with Neuroendocrine Neoplasms. It was a packed programme this year and it was especially great to have some really eminent speakers from the global NET community, including Marianne Pavel from Germany, who gave an amazing and comprehensive talk on ‘Personalised Medicine – Which Treatment for Whom’. She had no definitive answers, but pushed for the urgent need for more earlier predictive markers to understand which treatment would work best in patients. Other international speakers were Lisa Bodei from the USA, Eric Baudin from France and Nicola Fazio from Italy.

It was also so encouraging to have had 12 applications for the NPF/UKINETs research grant this year and to have 2 winners! One of the winners is part of the team running the Tracer-X Lung Cancer Project and we are delighted that Lung NENs will now be included in the cohort. The TRACERx (TRAcking Cancer Evolution through therapy (Rx)) lung study is a multi-million pound research project taking place over nine years, which will transform our understanding of non-small cell lung cancer (NSCLC) and take a practical step towards an era of precision medicine. The study will uncover mechanisms of cancer evolution by analysing the intratumour heterogeneity in lung tumours from approximately 850 patients and tracking its evolutionary trajectory from diagnosis through to relapse. At £14 million, it’s the biggest single investment in lung cancer research by Cancer Research UK, and the start of a strategic UK-wide focus on the disease, aimed at making real progress for patients.
The other worthy winner was Kate Lines who works with Professor Raj Thakker, and will continue her work on the molecular genetic study of pancreatic neuroendocrine neoplasms.

May we take this opportunity to wish all our friends around the world congratulations on the all the work they have done to support the NET community, and hope you all have a peaceful Christmas.